Insulin Resistance & Weight Gain
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Insulin resistance is one of the most common drivers of weight gain and weight loss resistance. It creates a cycle that's difficult to break through diet alone.
Overview
Insulin resistance occurs when cells don't respond normally to insulin, causing the pancreas to produce more insulin to compensate. Elevated insulin promotes fat storage and makes fat burning difficult.
Signs and Symptoms
- Difficulty losing weight despite caloric restriction
- Abdominal weight gain
- Sugar cravings and energy crashes
- Fatigue after meals
- Elevated fasting glucose or A1C
- Skin tags or acanthosis nigricans
Common Questions
Does insulin resistance go away with weight loss?
Often, yes — weight loss, particularly of visceral fat, can significantly improve insulin sensitivity. GLP-1 medications both help with weight loss AND directly improve insulin sensitivity.
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Medical Disclaimer: The information on this page is provided for educational purposes only and does not constitute medical advice. OakMD is a telemedicine platform. All treatments are prescription-based, subject to provider review, and may not be appropriate for all individuals. A licensed provider will evaluate your medical history and determine eligibility. Consult a qualified healthcare professional before starting any new treatment.